PCP Drug Urine Test Cassette

PCP Drug Urine Test Cassette
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Product Details

PCP Drug Urine Test Cassette


1. Product Details

Product Name: The PCP Drug Urine Test Cassette

Format: Cassette

Cut-off: 25ng/mL(customized)

Specimen: Urine

Storage: 2-30°C

2. Summary

Phencyclidine, also known as PCP or Angel Dust, is a hallucinogen that was first marketed as a surgical anesthetic in the 1950’s. It was removed from the market because patients receiving it became delirious and experienced hallucinations.

Phencyclidine is used in powder, capsule, and tablet form. The powder is either snorted or smoked after mixing it with marijuana or vegetable matter. Phencyclidine is most commonly administered by inhalation but can be used   intravenously, intranasally, and orally. After low doses, the user thinks and acts swiftly and experiences mood swings from euphoria to depression. Self-injurious behavior is one of the devastating effects of Phencyclidine.

PCP can be found in urine within 4 to 6 hours after use and will remain in urine for 7 to 14 days, depending on factors such as metabolic rate, user’s age, weight, activity, and diet. 1 PCP is excreted in the urine as unchanged drug (4% to 19%) and conjugated metabolites (25% to 30%). 

3. Principle

The PCP Drug Urine Test Cassette is an immunoassay based on the principle of competitive binding. Drugs that may be present in the urine specimen compete against the drug conjugate for binding sites on the antibody.

During testing, a urine specimen migrates upward by capillary action. Phencyclidine, if present in the urine specimen below 25 ng/mL, will not saturate the binding sites of the antibody in the test device. The Phencyclidine conjugate will be captured by antibody and a visible colored line will show up in the test line region. The colored line will not form in the test line region if the Phencyclidine level exceeds 25 ng/mL because it will saturate all the binding sites of anti-Phencyclidine antibodies.

A drug-positive urine specimen will not generate a colored line in the test line region (T) because of drug competition, while a drug-negative urine specimen will generate a line in the test line region because of the absence of drug competition. To serve as a procedural control, a colored line will always appear at the control line region, indicating that proper volume of specimen has been added and membranewicking has occurred.

4. Directions for Use

Allow the test device, urine specimen and/or controls to reach room temperature (15-30°C) prior to testing.

(1)Bring the pouch to room temperature before opening it. Remove the test device from the sealed pouch and use it as soon as possible.

(2)Place the test device on a clean and level surface. Hold the dropper vertically and transfer 3 full drops of urine (approx. 100μl) to the specimen well (S) of the test device, and then start the timer. Avoid trapping air bubbles in the specimen well (S). See the illustration below.

(3)Wait for the colored line(s) to appear. The result should be read at 5 minutes. Do not interpret the result after 10 minutes.

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5. Results

Please refer to illustration above.

6.Effect of the Urinary pH

The pH of an aliquoted negative urine pool was adjusted to a pH range of 5 to 9 in 1 pH unit increments and spiked with Phencyclidine to 12.5 ng/mL and 37.5ng/mL. The spiked, pH-adjusted urine was tested with the PCP One Step Phencyclidine Test Device in duplicate and interpreted according to the package insert. The results demonstrate that varying ranges of pH does not interfere with the performance of the test.

Hangzhou Laihe Biotech Co., Ltd

Address: Room 521 Floor 5 & Floor 1,Building No. 2B,Tianhe High-Tech Park,No. 688,Bin'an Road,Changhe Sub-district,Binjiang District,Hangzhou City,Zhejiang Province,China

Contact: Helen

Tel: +86-571-86658003

Fax: +86-571-86658000

E-mail: office@lyher.com

Zip:310052

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