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Cardiac marker POCT status quo(一)

Feb 16, 2018

The vast majority of coagulation analysis is sent to the laboratory after blood collection by the automated coagulation analyzer for testing, turnaround time, delivery and storage improperly easily affect the specimen quality. POCT instrument came into being, ACT is the most widely used indicator, mainly used in clinical departments, a drop of peripheral blood to obtain the approximate effect of heparin anticoagulant. Followed by the INR, in foreign countries have developed to blood glucose as the development of the patient self-test phase, which greatly facilitates the therapeutic monitoring, its feasibility and practicality is also confirmed in a special anticoagulation clinic. It may be premature to carry out self-tests in the country at this moment. We only discuss how to achieve good clinical application.

Prothrombin time (PT) and INR POCT

Oral anticoagulant therapy is one of the most effective ways to prevent thromboembolic diseases, especially in the prevention of atrial fibrillation associated with stroke, heart valve replacement and postoperative venous thrombosis prevention. The significant clinical effect has led to a substantial increase in the number of patients receiving warfarin therapy and the United Kingdom has grown at a rate of almost 10% annually. In addition, due to diet and drug metabolism and other reasons, the patient's INR may not remain static, so the establishment of long-term monitoring of INR mechanism is essential. The INR was measured at dose-adjusted intervals at least once a week until the results were stable. Increasing the frequency of monitoring will help stabilize INRs within therapeutic limits. In the face of huge workload pressure, more and more INR POCT products appear in domestic and foreign markets.

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