Marijuana main effective chemical composition is tetrahydrocannabinol (THC), and THC has mental and physiological activity after smoking or oral administration. The history of human consumption of marijuana has been more than a thousand years. The use of drugs and religion has increased in the 20th century.
Marijuana dependence is mainly based on psychological dependence, physical dependence is lighter, and tolerance is not easily generated. Usually a small inhalation or intermittent use of large doses does not produce withdrawal symptoms, withdrawal reactions are more common in areas with a higher dose of widely used. Suddenly disabled can occur agitation, anxiety, loss of appetite, insomnia, decreased body temperature, or even chills, fever, tremors. It generally disappears after 4 to 5 days.