Hepatitis C virus, referred to as hepatitis C and hepatitis C, is a viral hepatitis caused by hepatitis C virus (HCV) infection. It is mainly transmitted by blood transfusion, acupuncture, and drug use. According to the World Health Organization, the world The infection rate of HCV is about 3%. It is estimated that about 180 million people are infected with HCV, and about 35,000 new cases of hepatitis C occur each year. Hepatitis C is a global epidemic that can lead to chronic inflammation, necrosis and fibrosis in the liver, and some patients can develop cirrhosis or even hepatocellular carcinoma (HCC). The mortality associated with HCV infection (hepatic failure and death from hepatocellular carcinoma) will continue to increase in the next 20 years, which is extremely harmful to the health and life of patients and has become a serious social and public health problem.
Hepatitis C virus infection is the root cause of the disease. Under the influence of external factors, such as drinking alcohol, fatigue, long-term use of drugs with hepatotoxicity, can promote the development of the disease. The pathological changes of hepatitis C are very similar to those of hepatitis B, with hepatocyte necrosis and lymphocyte infiltration. Chronic hepatitis can occur in the portal area fibrous tissue hyperplasia, severe cases can form pseudolobules that become cirrhosis.