Syphilisis a chronic, systemic sexually transmitted disease caused by the pale (syphilis) spirochete. It is mainly transmitted through the sexual route, can be clinically expressed as primary syphilis, secondary syphilis, tertiary syphilis, latent syphilis and congenital syphilis (fetal transmission syphilis).
Syphilis is endemic in the world. According to WHO estimates, there are about 12 million new cases every year in the world, mainly in South Asia, Southeast Asia and sub-Saharan Africa. Syphilis is a disease unique to humans. Patients with dominant and recessive syphilis are the source of infection. Sexual contact is the main route of transmission of syphilis, accounting for more than 95%. Pregnant women with syphilis can be transmitted to the fetus through the placenta.