As a very sensitive indicator of acute phase response, plasma CRP concentration rapidly increased significantly in acute myocardial infarction, trauma, infection, inflammation, surgery, and tumor infiltration, up to 2000 times normal.
(1) Acute inflammation or tissue necrosis, such as severe trauma, surgery, acute infection, etc.: CRP often rises sharply within a few hours, and rises before erythrocyte sedimentation rate increases. CRP also returns to normal before erythrocyte sedimentation. The CRP concentration of the operator decreased 7-10 days after surgery, otherwise it may indicate infection or complicated thrombosis;
(2) Acute myocardial infarction: increased 24-48h, decreased after 3 days, returned to normal after 1-2 weeks;
(3) acute rheumatic fever, rheumatoid arthritis, systemic lupus erythematosus, bacterial infection, extensive tumor metastasis, active tuberculosis;
(4) CRP does not increase when the virus is infected;
(5) C-reactive protein can be used as an indicator for observing rheumatism and predicting the relative risk of myocardial infarction