Dengue fever is a mosquito-borne flavivirus found in tropical and subtropical regions of the world, mostly in urban and semi-urban areas. The bitten Aedes mosquito spreads the disease. It is the fastest-growing arbovirus disease and is currently prevalent in more than 100 countries, resulting in 40% of the world's population living in areas with high dengue fever. It is caused by one of four different serotypes (dengue 1-4). Although the first infection with one of the four dengue serotypes is usually not severe or asymptomatic, individuals exposed to another serotype in subsequent years are more susceptible to severe dengue. Non-serious dengue fever often manifests as flu-like illness, with symptoms including high fever, severe headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, gland swelling or rash. Severe dengue fever, including dengue hemorrhagic fever or dengue shock syndrome, characterized by severe abdominal pain, persistent vomiting, shortness of breath, bleeding gums, fatigue, restlessness, and vomiting with blood, and may be due to plasma leakage, fluid accumulation, Fatal due to respiratory distress, severe bleeding or organ damage. Although there is no specific treatment for dengue fever, proper case management can result in a case fatality of less than 1%. In the case of poor management, the mortality rate of severe dengue patients can be as high as 20%.