Troponin is a marker of myocardial injury and necrosis, and has important clinical significance for the diagnosis and risk stratification of acute myocardial infarction. Increased troponin value suggests myocardial injury, which can be seen in acute myocardial infarction, unstable angina pectoris, pulmonary infarction, heart failure and other diseases that cause myocardial injury such as pancreatitis and connective tissue diseases. The higher the value, the wider the damage range. In patients with acute myocardial infarction, the release begins at 3 to 6 hours, peaks at 10 to 24 hours, and the normal time cTnT and cTnI are 10 to 15 days and 5 to 7 days, respectively; some patients with renal insufficiency may also appear elevated.
Elevated troponin combined with is chemic evidence is helpful for the early diagnosis and treatment of type I myocardial infarction; mastering the change of troponin is helpful for the differential diagnosis of troponin elevation. Such as strenuous myocardial injury caused by strenuous exercise, tachycardia, acute pulmonary embolism, etc., cTn may appear transient increase, return to normal within 1-2 days; heart failure caused by chronic increase in cTn, these characteristics Both help to identify with myocardial infarction.